Key points Humans—and other complex multicellular organisms—have systems of organs that work together, carrying out processes that keep us alive. The body has levels of organization that build on each other. Cells make up tissues, tissues make up organs, and organs make up organ systems.
Research News April Five cavaliers are diagnosed with congenital diaphragmatic hernias and tension gastrothorax. All of the affected cavaliers were intact males, four of them between 2.
The cases occurred over a period of 12 years. The symptoms were rapid breathing and shortness of breath. In all of the dogs, chest x-rays showed a gas—fluid-filled structure on the left side of the chest, which was found to be the stomach see photo at rightwith some degree of lung collapse and shift to the opposite side.
The clinicians determined that the dogs developed "tension gastrothorax", which describes the stomach herniating through a congenital diaphragmatic defect into the thorax and distended due to being filled with trapped air.
One of the CKCSs was euthanized, and surgery was performed on the other four.
The hernias were repaired and all four of the surviving dogs recovered successfully. Genetically inherited disease in CKCS includes mitral valve disease, syringomyelia, congenital and juvenile cataract and multi-focal retinal dysplasia. Based on this report, CKCS could also be a breed predisposed to pleuroperitoneal diaphragmatic hernia, but extensive breeding studies would be necessary to evaluate this hypothesis.
Interestingly, all the cases were male, suggesting the possibility of a sex chromosomal mode of inheritance. Cavalier with severe periodontal disease develops Pasteurella Multocida meningoencephalomyelitis. Tun [right], Leontine Benedicenti, Evelyn M. Galban report on a 5-year-old spayed female cavalier King Charles spaniel with severe periodontal disease which had developed Pasteurella Multocida meningo-encephalomyelitis causing signs of a neurological disorder.
Based on cerebrospinal fluid and blood culture, as well as response to therapy, they opine that the severe periodontal disease led to a bacteremia causing hematogenous seeding of a bacterial meningitis originating at the disrupted blood—spinal cord barrier. Cavaliers rank 11th in diagnosis of arthritis in UK study of most frequently affected breeds.
Meeson, David Sargan, Jennifer F. Summers, Helen Zulch, Lisa M. Collins [right] examining all reported cases of osteoarthritis in a UK dog population under primary veterinary care duringfound that 2.
This made the CKCS the 11th most frequently affected breed in the study.
Of 10, cavaliers in the study, were diagnosed with osteoarthritis. The most frequently affected breeds were: The overall average of all dogs diagnosed with osteoarthritis was 2.
UK study of dogs shows three years between core vaccine boosters provide long-lived immunity. In a January article by a team of UK researchers R. Day [right]they used an in-practice test kit to detect protective serum antibody against canine distemper virus, canine adenovirus and canine parvovirus type 2 in dogs of various breeds.
They report finding that They surmisded that the small number of other dogs may have had waning of previous serum antibody or may have been rare genetic non-responders to that specific antigen. In-practice serological test kits are a valuable tool for informing decision-making about canine core revaccination.
Cavalier with facial nerve paralysis is successfully treated with laser treatment at acupuncture points. In an October abstractDr. Dustin Dees right of Austin, Texas reports successfully treating a cavalier King Charles spaniel suffering from idiopathic facial nerve paralysis by using continuous wave laser treatments at four acupuncture sites corresponding to a branch of the facial nerve.
The method is called "photobiomodulation". Treatments were performed twice a week for five weeks. The results were successful. The dog's blinking ability substantially improved, and corneal dryness resolved with marked improvement of the dog's Schirmer testing.
Cavaliers were at highest risk of severe reaction to incompatible blood transfusions, in Italian study. In a September article by a team of Italian veterinary blood specialists Anyela Andrea Medina Valentin [right], Alessandra Gavazza, George Lubasthey studied 7, dogs, including cavalier King Charles spaniels, to determine the potential sensitization risk to dogs receiving blood transfusions consisting of the Dog Erythrocyte Antigen DEA 1 blood group.
Following a second transfusion of DEA 1 positive blood, a dog which is highly sensitized to DEA 1 positive may develop an acute reaction, including fever, pigmenturia, and lethargy, and its packed cell volume PCV will not rise as expected.
Death may result from such a mis-matched second transfusion. See this May article. In this Italian study, they found that CKCSs were among the few breeds having the highest percentage likelihood to become sensitized Research News.
April Five cavaliers are diagnosed with congenital diaphragmatic hernias and tension leslutinsduphoenix.com an April article, UK and Swiss researchers (M. Rossanese, M. Pivetta, N. Pereira, R. Burrow) reported on five separate cases of cavalier King Charles spaniels diagnosed with a congential defect in the diaphram causing the stomach and/or other abdominal organs to.
Learn about the main tissue types and organ systems of the body and how they work together. In humans, the kidneys are located high in the abdominal cavity, one on each side of the spine, and lie in a retroperitoneal position at a slightly oblique angle.
The asymmetry within the abdominal cavity, caused by the position of the liver, typically results in the right kidney being slightly lower and smaller than the left, and being placed slightly more to the middle than the left kidney. The peptide hormones page provides an overview of structure and function of numerous classes of protein-derived hormones which exert a wide-range of autocrine, paracrine, and endocrine functions.
Vitamin D’s Role in Health — Deterministic or Indeterminate? By Stephanie Dunne and Jenna A. Bell, PhD, RD Today’s Dietitian. Ghrelin is an important hormone when it comes to health. It’s not “good” or “bad” but is more dependent on the person.
Ghrelin plays a role in cognitive function, gut function, inflammation, metabolism, weight, fertility and emotional states, to name a few.